Throughout the world, the high popularity is enjoyed of generic Levitra (Vardenafil). Reviews show that this medicine is very mild effecting on the male reproductive system and almost never cause side effects. When you first purchase Vardenafil many men are confused by a very big difference between the prices in usual pharmacies and online stores. It has nothing to do with the quality of medicines. The difference in cost is due to the place of manufacture of the drug.
During the development process of the active substance has been spent a lot of money. That is why the creators of the drug set a high selling price. Costs got out pretty quickly, but the price does not fall. This situation is not conducive to the spread of Vardenafil. Most men could not afford this medication. Levitra began manufacturing on Indian pharmaceutical factories. He is the absolute analogue of the “original”, having a lower cost. In addition, sales of generic Levitra carried out only through Internet, allowing even more to reduce the price.
High efficiency in the treatment of erectile dysfunction is shown by Levitra 20 mg. The action of the drug is based on inhibition of a specific enzyme phosphodiesterase of type 5. This material begins to produce after orgasm. With his help penis goes into a relaxed state. When the reproductive system begins to be excited, in the cavernous bodies released nitric oxide (NO), involved in the formation of cyclic guanosine monophosphate. The muscles disposed in the cavernous bodies; do not allow blood to enter inside. CGMP relaxes smooth muscles, thereby providing access to the blood and an increase in the corpora cavernosa.
The Drug`s Action
He is quickly absorbed by the body and starts to act within 20-30 seconds. Many say that the erection occurs in 15-20 minutes. But in most cases the effect is noticeable after 30-40 minutes. The action of the drug can last from 6 to 8 hours. It depends on the psychological and physiological state of man. The maximum number of Vardenafil in the plasma is commonly observed after 1-2 h. After this the active substance is transported to the liver and is converted into inactive metabolites. They are removed from the body through fecal masses. Only a very small amount (up to 15%) is output from the kidneys.
The initial reception of the drug Levitra dose should not exceed 1/2 of the pill (10 mg). Studies show that 65% of this amount of Vardenafil is enough to maintain a stable erection. If the effect is completely absent or is insufficient, the dosage is increased to a whole pill (20 mg). This amount of Vardenafil helps to restore full control of the erection. Men older than 65 years, as well as people who are in a weakened state, are recommended to use 5 mg (1/4 pills). Between the techniques it should not take place less than 24 hours maximum for daily dose of generic Levitra – 20 mg.
Price Policy and Side Effects
The price of the drug contributed to its widespread use. However, be aware that sometimes Vardenafil can cause unwanted reactions:
- redness of the face;
- the pressure in the temples;
- nasal congestion, runny nose;
Side effects may occur immediately or shortly after receiving Vardenafil. Reviews say that they usually disappear within a few hours.